What is the Lasmiditan succinate (USAN)?

Lasmiditan succinate (USAN) is , while it's Molecular Formula is 0C 4 H 6 O 4 *C 19 H 18 F 3 N 3 O 2 . Used in Pharmaceutical Industry: Lasmiditan succinate (USAN) is used as a migraine treatment for [application reason] the acute treatment of migraine with or without aura in adults. Its selective action on the 5-HT1F receptors and lack of vasoconstriction make it a preferred option for patients with cardiovascular conditions. Used in Migraine Management: Lasmiditan succinate (USAN) is used as a therapeutic agent for [application reason] providing relief from the symptoms of migraine attacks. Its mechanism of action targets the trigeminal nerve pathway, offering an effective treatment option for those suffering from migraines. Used in Cardiovascular Health Considerations: Lasmiditan succinate (USAN) is used as a safer alternative for [application reason] treating migraines in patients with cardiovascular conditions, as it does not cause vasoconstriction, a common side effect of other migraine medications. This makes it a more suitable choice for individuals with heart-related health concerns.

What is the CAS number for Lasmiditan succinate (USAN)?

The CAS number of Lasmiditan succinate (USAN) is 439239-92-6.

What is Lasmiditan succinate (USAN) (439239-92-6) used for?

Lasmiditan succinate (USAN) is a novel, highly selective serotonin receptor agonist specifically designed for the acute treatment of migraine with or without aura in adults. Developed by Eli Lilly and Company, it has been approved by the US Food and Drug Administration (FDA) for this purpose. It functions by targeting the 5-HT1F receptors located in the trigeminal nerve pathway, and does not cause vasoconstriction, making it a suitable treatment option for patients with cardiovascular conditions. It is commercially known as Reyvow.

What is the Lasmiditan succinate (USAN)?

Lasmiditan succinate (USAN) is , while it's Molecular Formula is 0C 4 H 6 O 4 *C 19 H 18 F 3 N 3 O 2 . Used in Pharmaceutical Industry: Lasmiditan succinate (USAN) is used as a migraine treatment for [application reason] the acute treatment of migraine with or without aura in adults. Its selective action on the 5-HT1F receptors and lack of vasoconstriction make it a preferred option for patients with cardiovascular conditions. Used in Migraine Management: Lasmiditan succinate (USAN) is used as a therapeutic agent for [application reason] providing relief from the symptoms of migraine attacks. Its mechanism of action targets the trigeminal nerve pathway, offering an effective treatment option for those suffering from migraines. Used in Cardiovascular Health Considerations: Lasmiditan succinate (USAN) is used as a safer alternative for [application reason] treating migraines in patients with cardiovascular conditions, as it does not cause vasoconstriction, a common side effect of other migraine medications. This makes it a more suitable choice for individuals with heart-related health concerns.

What is the CAS number for Lasmiditan succinate (USAN)?

The CAS number of Lasmiditan succinate (USAN) is 439239-92-6.

What is Lasmiditan succinate (USAN) (439239-92-6) used for?

Lasmiditan succinate (USAN) is a novel, highly selective serotonin receptor agonist specifically designed for the acute treatment of migraine with or without aura in adults. Developed by Eli Lilly and Company, it has been approved by the US Food and Drug Administration (FDA) for this purpose. It functions by targeting the 5-HT1F receptors located in the trigeminal nerve pathway, and does not cause vasoconstriction, making it a suitable treatment option for patients with cardiovascular conditions. It is commercially known as Reyvow.

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Molecular Formula: 0C₄H₆O₄*C₁₉H₁₈F₃N₃O₂
Molecular Weight: 436.411
PSA： 206.18000
LogP: 7.13100

439239-92-6 Relevant articles

2,2-DIMETHYL-N-[6-(1-METHYL-PIPERIDIN-4-CARBONYL)-PYRIDIN-2-YL]-PROPIONAMIDE, METHOD FOR PREPARING (6-AMINO-PYRIDIN-2-YL)-(1-METHYL-PIPERIDIN-4-YL)-METHANONE USING SAID COMPOUND, AND USE OF SAID COMPOUND IN THE PREPARATION OF LASMIDITAN

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Page/Page column 22, (2021/01/23)

The present invention relates to a new i...

PROCESS FOR PREPARATION OF LASMIDITAN

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Paragraph 0094, (2021/08/06)

The present invention relates to a proce...

PROCESSES AND INTERMEDIATE FOR THE LARGE-SCALE PREPARATION OF 2,4,6-TRIFLUORO-N-[6-(1-METHYL-PIPERIDINE-4-CARBONYL)-PYRIDIN-2-YL]-BENZAMIDE HEMISUCCINATE, AND PREPARATION OF 2,4,6-TRIFLUORO-N-[6-(1-METHYL-PIPERIDINE-4-CARBONYL)-PYRIDIN-2-YL]-BENZAMIDE ACE

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Page/Page column 37-40, (2021/01/29)

The embodiments of present invention pro...

PROCESS FOR PREPARATION OF LASMIDITAN

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Paragraph 0187-0190, (2020/06/01)

The present invention relates to a proce...

439239-92-6 Process route

: 439239-90-4
Lasmiditan

: 110-15-6
succinic acid

: 439239-92-6
2,4,6-trifluoro-N- [6-(1-methylpiperidine-4-carbonyl)-2-pyridyl]benzamide hemisuccinate

Conditions

Conditions	Yield
In ethanol; at 20 - 80 ℃; Inert atmosphere;	85%
In ethanol; at 70 - 78 ℃; for 4h;	78.2%

: 5570-77-4
4-chloro-1-methylpiperidine

: 110-15-6
succinic acid

: C₁₇H₁₄F₃N₃O₃

: 439239-92-6
2,4,6-trifluoro-N- [6-(1-methylpiperidine-4-carbonyl)-2-pyridyl]benzamide hemisuccinate

Conditions

Conditions	Yield
4-chloro-1-methylpiperidine; With iodine; magnesium; In tetrahydrofuran; for 0.5h; Inert atmosphere; C₁₇H₁₄F₃N₃O₃; In tetrahydrofuran; at -10 - -5 ℃; for 0.5h; Inert atmosphere; succinic acid; In isopropyl alcohol; at 25 - 50 ℃;	43.55%