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1.What is the HBTU ?
peptide coupling reagent that reduces racemization
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2592-95-2
benzotriazol-1-ol
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-
N,N,N',N'-tetramethylchloroformamidinium hexafluorophosphate
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94790-37-1
O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate
| Conditions | Yield |
|---|---|
|
With
triethylamine;
In
dichloromethane;
|
100%
|
-
-
632-22-4
tetramethylurea
-
-
94790-37-1
O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate
| Conditions | Yield |
|---|---|
|
Multi-step reaction
with
3
steps
1: phosgene / toluene / 0.25 h
2: aq. ammonium hexafluorophosphate / CH2
Cl2
3: 100 percent / N(C2
H5
)3 / CH2
Cl2
With
phosgene; ammonium hexafluorophosphate; triethylamine;
In
dichloromethane; toluene;
|
|
|
Multi-step reaction
with
2
steps
1: oxalyl chloride
2: KPF6
,KCl
With
potassium hexafluorophosphate; oxalyl dichloride; potassium chloride;
|
2.What is the CAS number for HBTU ?
The CAS number of HBTU is 94790-37-1.
More information of HBTU 94790-37-1 are:
|
CAS?Number |
94790-37-1 |
|
Melting Point |
200- 202 °C |
|
Flash Point |
200°C |
|
HS CODE |
HOSPHATE PRODUCT IDENTIFICATION |
|
PSA |
59.78000 |
|
LogP |
3.43200 |
3.What are another words for HBTU ?
Synonyms?for?HBTU 94790-37-1:o-Benzotriazol-1-yl-N,N,N',N'-tetramethyluronium hexafluorophosphate;o-Benzotriazol-1-yl-tetramethyluronium hexafluorophosphate;HBTU;
4.What is the molecular formula of HBTU?
The chemical formula of ?HBTU is?C11H16N5O. PF6 which containing 11 Carbon atoms,16 Hydrogen atoms,5 Nitrogen atoms,1 Phosphorus atoms and 6 Fluorine atoms,and the molecular weight of??HBTU?is 379.245.
5.What is HBTU (94790-37-1) used for?
HBTU, also known as 2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate, is a widely used coupling reagent in the field of organic chemistry and peptide synthesis. It is known for its ability to promote the formation of peptide bonds while effectively suppressing racemization, which is the unwanted conversion of L-amino acids to their D-isomers during the synthesis process.
InChI:InChI=1/C11H16N5O.F6P/c1-14(2)11(15(3)4)17-16-10-8-6-5-7-9(10)12-13-16;1-7(2,3,4,5)6/h5-8H,1-4H3;/q+1;-1
Relevant articles related to HBTU:
|
Article |
Source |
|
Method of forming N-protected amino acid thiohydantoins |
- , (2008/06/13) |
|
O-benzotriazolyl-N,N,N',N'-tetramethyluronium hexafluorophosphate as coupling reagent for the synthesis of peptides of biological interest |
Dourtoglou,Gross , p. 572 - 574 (2007/10/02) |
6.Buy HBTU with the best price .
ShanDong XinDa Chemical CO.,LTD is a quality supplier of HBTU. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on HBTU 94790-37-1.
