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99% Purity Commercial production 2-Amino-5-chloro-2'-fluorobenzophenone 784-38-3 with Cheapest Price

  • Molecular Formula: C13H9ClFNO
  • Molecular Weight: 249.672
  • Appearance/Colour: yellow fine powder 
  • Melting Point: 93-97 °C 
  • Boiling Point: 432.2 °C at 760 mmHg 
  • PKA: -1.05±0.10(Predicted) 
  • Flash Point: 215.2 °C 
  • PSA: 43.09000 
  • Density: 1.342 g/cm3 
  • LogP: 3.87350 

784-38-3 Relevant articles

Iron-Promoted Construction of Indoles via Intramolecular Oxidative C-N Coupling of 2-Alkenylanilines Using Persulfate

Li, Yudong,Li, Yuehui,Luo, Shuping,Wang, Menglan,Wu, Qing-An

supporting information, p. 3085 - 3090 (2019/08/07)

Indole scaffold synthesis relies primari...

Cu(I)-Catalyzed Coupling and Cycloisomerization of Diazo Compounds with Terminal Yne-Alkylidenecyclopropanes: Synthesis of Functionalized Cyclopenta[ b]naphthalene Derivatives

Li, Peng-Hua,Yu, Liu-Zhu,Zhang, Xiao-Yu,Shi, Min

, p. 4516 - 4520 (2018/08/09)

A Cu(I)-catalyzed coupling and cycloisom...

Palladium-catalyzed direct addition of arylboronic acids to 2-aminobenzonitrile derivatives: Synthesis, biological evaluation and in silico analysis of 2-aminobenzophenones, 7-benzoyl-2-oxoindolines, and 7-benzoylindoles

Chen, Jiuxi,Ye, Leping,Su, Weike

supporting information, p. 8204 - 8211 (2015/01/08)

A palladium-catalyzed direct addition of...

Synthesis of 2-aminobenzophenone derivatives and their anticancer activity

Cortez-Maya,Cortes Cortes,Hernandez-Ortega,Apan, T. Ramirez,Martinez-Garcia

experimental part, p. 46 - 54 (2011/10/31)

A number of 2-aminobenzophenones have be...

784-38-3 Process route

flurazepam
17617-23-1

flurazepam

2-amino-5-chloro-2'-fluorobenzophenone
784-38-3

2-amino-5-chloro-2'-fluorobenzophenone

7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1,4-benzodiazepin-2(2H)-one
2886-65-9

7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1,4-benzodiazepin-2(2H)-one

Conditions
Conditions Yield
With hydrogenchloride; multistep reaction: biotransformation, acid hydrolysis;
2-amino-5-chlorobenzonitrile
5922-60-1

2-amino-5-chlorobenzonitrile

o-fluorophenylboronic acid
1993-03-9

o-fluorophenylboronic acid

2-amino-5-chloro-2'-fluorobenzophenone
784-38-3

2-amino-5-chloro-2'-fluorobenzophenone

Conditions
Conditions Yield
With 5,5'-dimethyl-2,2'-bipyridine; methanesulfonic acid; palladium(II) trifluoroacetate; water; In 2-methyltetrahydrofuran; at 80 ℃; for 36h; Schlenk technique;
64%
With [2,2]bipyridinyl; methanesulfonic acid; palladium(II) trifluoroacetate; In tetrahydrofuran; water; at 80 ℃; for 36h;

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