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Chemical plants supply high-quality 1-(2,6-Dichlorophenyl)indolin-2-one 15362-40-0 in bulk

  • Molecular Formula: C14H9Cl2NO
  • Molecular Weight: 278.138
  • Melting Point: 115-119°C 
  • Boiling Point: 488.6 ºC at 760 mmHg 
  • PKA: -4.85±0.20(Predicted) 
  • Flash Point: 249.3 ºC 
  • PSA: 20.31000 
  • Density: 1.432 g/cm3 
  • LogP: 4.27920 

1-(2,6-Dichlorophenyl)indolin-2-one(Cas 15362-40-0) Usage

InChI:InChI=1/C14H9Cl2NO/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(17)18/h1-7H,8H2

15362-40-0 Relevant articles

Vilsmeier reagent, NaHSe and diclofenac acid chloride: One-pot synthesis of a novel selenoindolinone with potent anticancer activity

Aydillo, Carlos,Plano, Daniel,Ruberte, Ana Carolina,Sanmartín, Carmen,Sharma, Arun K.

, p. 38404 - 38408 (2020)

An effective and straightforward synthes...

Synthesis, ex vivo and in vitro hydrolysis study of an indoline derivative designed as an anti-inflammatory with reduced gastric ulceration properties

Chung, Man Chin,Dos Santos, Jean Leandro,Oliveira, Ednir Vizioli,Blau, Lorena,Renato Farina Menegon,Peccinini, Rosangela Goncalves

, p. 3187 - 3197 (2009)

The compound 1-(2,6-dichlorophenyl)indol...

Stability of diclofenac sodium in the inclusion complex with β-cyclodextrin in the solid state

Cwiertnia, Barbara,Hladon, Teresa,Stobiecki, Maciej

, p. 1213 - 1218 (1999)

The aim of this study was to characteriz...

Diclofenac sodium injection sterilized by autoclave and the occurrence of cyclic reaction producing a small amount of impurity

Roy, Jiben,Islam, Mafizul,Khan, Anowar H.,Das, Subodh C.,Akhteruzzaman,Deb, Ajay K.,Mahbub Alam

, p. 541 - 544 (2001)

A known impurity is formed in the produc...

Synthesis method of diclofenac sodium

-

Paragraph 0024; 0026; 0028; 0030; 0032; 0034, (2021/09/21)

The invention discloses a synthesis meth...

Diclofenac n-derivatives as therapeutic agents with anti-inflammatory and anti-cancer effect

Galisteo, Alberto,Jannus, Fatin,García-García, Amalia,Aheget, Houssam,Rojas, Sara,Lupia?ez, José A.,Rodríguez-Diéguez, Antonio,Reyes-Zurita, Fernando J.,Quílez Del Moral, José F.

, (2021/05/18)

A series of diclofenac N-derivatives (2,...

Degradation kinetics and mechanism of diclofenac by UV/peracetic acid

Fu, Yongsheng,Liu, Yiqing,Zhang, Li

, p. 9907 - 9916 (2020/03/23)

In this work, the degradation kinetics a...

Preparation method of 2-[(2, 6-dichlorophenyl) amino] sodium phenylacetate

-

Paragraph 0034-0034; 0038-0045, (2020/05/30)

The invention belongs to the field of ch...

15362-40-0 Process route

diclofenac sodium
15307-79-6

diclofenac sodium

1-(2,6-dichlorophenyl)indolin-2-one
15362-40-0

1-(2,6-dichlorophenyl)indolin-2-one

carbazole-1-acetic acid
131023-43-3

carbazole-1-acetic acid

2-[2-(phenylamino)phenyl]acetic acid
70172-33-7

2-[2-(phenylamino)phenyl]acetic acid

C<sub>13</sub>H<sub>7</sub>Cl<sub>2</sub>NO<sub>2</sub>

C13 H7 Cl2 NO2

4',5-Dihydroxydiclofenac
69002-86-4

4',5-Dihydroxydiclofenac

(8-hydroxy-9H-carbazol-1-yl)acetic acid

(8-hydroxy-9H-carbazol-1-yl)acetic acid

Conditions
Conditions Yield
With peracetic acid; In aq. phosphate buffer; pH=8.5; Reagent/catalyst; pH-value; Kinetics; UV-irradiation;
aceclofenac
89796-99-6

aceclofenac

1-(2,6-dichlorophenyl)indolin-2-one
15362-40-0

1-(2,6-dichlorophenyl)indolin-2-one

[2-(2,6-dichloroanilino)phenyl]acetic acid
15307-86-5

[2-(2,6-dichloroanilino)phenyl]acetic acid

2-(2-((2,6-dichlorophenyl)amino)phenyl)-2-oxoacetic acid
66156-75-0

2-(2-((2,6-dichlorophenyl)amino)phenyl)-2-oxoacetic acid

Conditions
Conditions Yield
With water; sodium hydroxide; for 12h; Reflux;

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    1-(2,6-dichlorophenyl)-3-(methylthio)oxindole

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    2,2-dimethyl-1,3-dioxolane

15362-40-0 Downstream products

  • 15307-79-6
    15307-79-6

    diclofenac sodium

  • 110326-34-6
    110326-34-6

    1-(2,6-Dichlorophenyl)-3-(dimethylaminomethylene)-6-formylindolin-2-one

  • 175983-50-3
    175983-50-3

    1-(2',6'-dichlorophenyl)-3-dimethylaminomethylene-2-indolinone

  • 172371-95-8
    172371-95-8

    1-(2',6'-dichlorophenyl)-3-(β-hydroxyethyl)aminomethylene-2-indolinone

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