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Chemical plants supply high-quality 1-(2,6-Dichlorophenyl)indolin-2-one 15362-40-0 in bulk
- Molecular Formula: C14H9Cl2NO
- Molecular Weight: 278.138
- Melting Point: 115-119°C
- Boiling Point: 488.6 ºC at 760 mmHg
- PKA: -4.85±0.20(Predicted)
- Flash Point: 249.3 ºC
- PSA: 20.31000
- Density: 1.432 g/cm3
- LogP: 4.27920
1-(2,6-Dichlorophenyl)indolin-2-one(Cas 15362-40-0) Usage
InChI:InChI=1/C14H9Cl2NO/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(17)18/h1-7H,8H2
15362-40-0 Relevant articles
Vilsmeier reagent, NaHSe and diclofenac acid chloride: One-pot synthesis of a novel selenoindolinone with potent anticancer activity
Aydillo, Carlos,Plano, Daniel,Ruberte, Ana Carolina,Sanmartín, Carmen,Sharma, Arun K.
, p. 38404 - 38408 (2020)
An effective and straightforward synthes...
Synthesis, ex vivo and in vitro hydrolysis study of an indoline derivative designed as an anti-inflammatory with reduced gastric ulceration properties
Chung, Man Chin,Dos Santos, Jean Leandro,Oliveira, Ednir Vizioli,Blau, Lorena,Renato Farina Menegon,Peccinini, Rosangela Goncalves
, p. 3187 - 3197 (2009)
The compound 1-(2,6-dichlorophenyl)indol...
Stability of diclofenac sodium in the inclusion complex with β-cyclodextrin in the solid state
Cwiertnia, Barbara,Hladon, Teresa,Stobiecki, Maciej
, p. 1213 - 1218 (1999)
The aim of this study was to characteriz...
Diclofenac sodium injection sterilized by autoclave and the occurrence of cyclic reaction producing a small amount of impurity
Roy, Jiben,Islam, Mafizul,Khan, Anowar H.,Das, Subodh C.,Akhteruzzaman,Deb, Ajay K.,Mahbub Alam
, p. 541 - 544 (2001)
A known impurity is formed in the produc...
Synthesis method of diclofenac sodium
-
Paragraph 0024; 0026; 0028; 0030; 0032; 0034, (2021/09/21)
The invention discloses a synthesis meth...
Diclofenac n-derivatives as therapeutic agents with anti-inflammatory and anti-cancer effect
Galisteo, Alberto,Jannus, Fatin,García-García, Amalia,Aheget, Houssam,Rojas, Sara,Lupia?ez, José A.,Rodríguez-Diéguez, Antonio,Reyes-Zurita, Fernando J.,Quílez Del Moral, José F.
, (2021/05/18)
A series of diclofenac N-derivatives (2,...
Degradation kinetics and mechanism of diclofenac by UV/peracetic acid
Fu, Yongsheng,Liu, Yiqing,Zhang, Li
, p. 9907 - 9916 (2020/03/23)
In this work, the degradation kinetics a...
Preparation method of 2-[(2, 6-dichlorophenyl) amino] sodium phenylacetate
-
Paragraph 0034-0034; 0038-0045, (2020/05/30)
The invention belongs to the field of ch...
15362-40-0 Process route
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15307-79-6
diclofenac sodium
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15362-40-0
1-(2,6-dichlorophenyl)indolin-2-one
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131023-43-3
carbazole-1-acetic acid
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70172-33-7
2-[2-(phenylamino)phenyl]acetic acid
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C13 H7 Cl2 NO2
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69002-86-4
4',5-Dihydroxydiclofenac
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(8-hydroxy-9H-carbazol-1-yl)acetic acid
| Conditions | Yield |
|---|---|
|
With
peracetic acid;
In
aq. phosphate buffer;
pH=8.5;
Reagent/catalyst;
pH-value;
Kinetics;
UV-irradiation;
|
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89796-99-6
aceclofenac
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15362-40-0
1-(2,6-dichlorophenyl)indolin-2-one
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15307-86-5
[2-(2,6-dichloroanilino)phenyl]acetic acid
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66156-75-0
2-(2-((2,6-dichlorophenyl)amino)phenyl)-2-oxoacetic acid
| Conditions | Yield |
|---|---|
|
With
water; sodium hydroxide;
for 12h;
Reflux;
|
15362-40-0 Upstream products
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3644-56-2
2-chloro-N-(2,6-dichlorophenyl)acetamide
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15308-01-7
2-chloro-N-(2',6'-dichlorophenyl)-N-phenylacetamide
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83281-94-1
1-(2,6-dichlorophenyl)-3-(methylthio)oxindole
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2916-31-6
2,2-dimethyl-1,3-dioxolane
15362-40-0 Downstream products
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15307-79-6
diclofenac sodium
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110326-34-6
1-(2,6-Dichlorophenyl)-3-(dimethylaminomethylene)-6-formylindolin-2-one
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175983-50-3
1-(2',6'-dichlorophenyl)-3-dimethylaminomethylene-2-indolinone
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172371-95-8
1-(2',6'-dichlorophenyl)-3-(β-hydroxyethyl)aminomethylene-2-indolinone